HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(2,6-Dichloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (3,4,4-Trifluoro-3-butenyl)malononitrile | HCID 22185753 | — |
| Reactant | Benzene, 2-(bromomethyl)-1,3-dichloro-5-(trifluoromethyl)- | HCID 22235045 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2,6-Dichloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile | HCID 22235066 | 52.1% |
Reaction Steps
Using 0.15 g of (3,4,4-trifluoro-3-butenyl)malononitrile, 5 ml of N,N-dimethylformamide, 38 mg of sodium hydride (60% in oil), and 0.27 g of 2,6-dichloro-4-(trifluoromethyl)benzylbromide, and according to the process described in the Production Example 1, there was obtained 0.18 g of 2-(2,6-dichloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile (the present compound (66)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-0b7bd32f3a8d47f2b9fd46b3083146c2 |
| Source note | uspto-grants-2008_07 |