HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(4-Cyanobenzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Reactant | (3,4,4-Trifluoro-3-butenyl)malononitrile | HCID 22185753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-Cyanobenzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile | HCID 22235016 | 63.2% |
Reaction Steps
Using 0.20 g of (3,4,4-trifluoro-3-butenyl)malononitrile, 5 ml of N,N-dimethylformamide, 50 mg of sodium hydride (60% in oil), and 0.25 g of α-bromo-p-tolunitrile, and according to the process described in the Production Example 1, there was obtained 0.21 g of 2-(4-cyanobenzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile (the present compound (68)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-a9f26522052c41c0ab13be38eb96bd6c |
| Source note | uspto-grants-2008_07 |