HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(2,2,3,3,4,4,4-Heptafluorobutyl)-2-(4-(trifluoromethyl)benzyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1H,1H-Heptafluorobutyl trifluoromethanesulphonate | HCID 2774894 | — |
| Reactant | (4-(Trifluoromethyl)benzyl)malononitrile | HCID 10656743 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2,2,3,3,4,4,4-Heptafluorobutyl)-2-(4-(trifluoromethyl)benzyl)malononitrile | HCID 22235021 | 8.1% |
Reaction Steps
Using 0.50 g of (4-(trifluoromethyl)benzyl)malononitrile, 5 ml of N,N-dimethylformamide, 59 mg of sodium hydride (60% in oil), and 0.77 g of 2,2,3,3,4,4,4-heptafluorobutyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 73 mg of 2-(2,2,3,3,4,4,4-heptafluorobutyl)-2-(4-(trifluoromethyl)benzyl)malononitrile (the present compound (77)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-7d7fdb5c38d145c0962da01aee68cf41 |
| Source note | uspto-grants-2008_07 |