HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Xylyl bromide → HCID 22235002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Xylyl bromide | HCID 7721 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-(3,3,3-Trifluoropropyl)malononitrile | HCID 22185761 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235002 | HCID 22235002 | 76% |
Reaction Steps
Using 0.19 g of 4-methylbenzyl bromide, 3 ml of N,N-dimethylformamide, 0.05 g of sodium hydride (60% in oil), and 0.17 g of (3,3,3-trifluoropropyl)malononitrile, and according to the process described in the Production Example 26, there was obtained 0.20 g of 2-(4-methylbenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (84)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07402691B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-6b907c477cef4a009bc44eda4da4dcc8 |
| Source note | uspto-grants-2008_07 |