HCID 786126, compound → HCID 22235013, compound

HRID 749613Notes

Reaction equation

HRID 749613 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][C:13]=1[F:14])[CH:5]=[C:6]([C:9]#[N:10])[C:7]#[N:8].[BH4-].[Na+]>C(O)C>[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][C:13]=1[F:14])[CH2:5][CH:6]([C:7]#[N:8])[C:9]#[N:10]

Participants

4

Reactant 2

HCID 786126HCID 786126, compoundHCID 4311764Sodium borohydride

Product 1

HCID 22235013HCID 22235013, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 10.0 g of (3,4-difluorobenzyliden)malononitrile, 200 ml of ethanol and 0.6 g of sodium borohydride, and according to the process described in the Reference Production Example 3, there was obtained 8.05 g of (3,4-difluorobenzyl)malononitrile (the intermediate (23)).

Sources & evidence

ORD record
ord-17b1a044188144c29d9dd98ac425f503
Source dataset
uspto-grants-2008_07
Patent number
US07402691B2

Reaction notes

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