Sodium borohydride → HCID 22235073, compound

HRID 749618Notes

Reaction equation

HRID 749618 reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([C:14]([F:17])([F:16])[F:15])[CH:11]=[C:10]([Cl:18])[C:3]=1[CH:4]=[C:5]([C:8]#[N:9])[C:6]#[N:7].[BH4-].[Na+]>C(O)C>[Cl:1][C:2]1[CH:13]=[C:12]([C:14]([F:15])([F:16])[F:17])[CH:11]=[C:10]([Cl:18])[C:3]=1[CH2:4][CH:5]([C:6]#[N:7])[C:8]#[N:9]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 22235079HCID 22235079, compound

Product 1

HCID 22235073HCID 22235073, compoundYield 96.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 1.0 g of (2,6-dichloro-4-(trifluoromethyl)benzyliden)malononitrile, 20 ml of ethanol and 0.03 g of sodium borohydride, and according to the process described in the Reference Production Example 3, there was obtained 0.97 g of (2,6-dichloro-4-(trifluoromethyl)benzyl)malononitrile (the intermediate (32)).

Sources & evidence

ORD record
ord-0832ddc87afd49e39b68ffe42de41d71
Source dataset
uspto-grants-2008_07
Patent number
US07402691B2

Reaction notes

Loading…