反应详情

A solution (50 ml) of 4-methanesulfonylbenzylamine (5.0 g) and 1,2-epoxypentane (2.8 g) in methanol was stirred at room temperature for 96 hrs. The reaction mixture was concentrated under reduced pressure, and the obtained residue was purified by silica gel column chromatography (ethyl acetate-ethyl acetate:methanol=10:1) to give the title compound (2.5 g).

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customthe obtained residue was purified by silica gel column chromatography (ethyl acetate-ethyl acetate:methanol=10:1)