Cyclohexanemethanol → HCID 69156840, compound

HRID 750202Notes

Reaction equation

HRID 750202 reaction equation
C(O[C:9]([N:11](C)[N:12]1[C:21]([C:22]([OH:24])=[O:23])=[C:20]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19]2[C:14](=[CH:15][CH:16]=[C:17]([Cl:31])[CH:18]=2)[C:13]1=[O:32])=O)C1C=CC=CC=1.[CH2:34]1[CH2:39][CH2:38][CH:37]([CH2:40]O)[CH2:36][CH2:35]1>>[CH:37]1([CH2:40][O:24][C:22]([C:21]2[N:12]([NH:11][CH3:9])[C:13](=[O:32])[C:14]3[C:19]([C:20]=2[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[CH:18][C:17]([Cl:31])=[CH:16][CH:15]=3)=[O:23])[CH2:38][CH2:39][CH2:34][CH2:35][CH2:36]1

Participants

3

Reactant 2

HCID 7507CyclohexanemethanolHCID 691557392-[(benzyloxycarbonyl)(methyl)amino]-6-chloro-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid

Product 1

HCID 69156840HCID 69156840, compound

Procedure

The present compound was synthesized by a method similar to that in Example 207 and using 2-[(benzyloxycarbonyl)(methyl)amino]-6-chloro-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (200 mg) and 4-cyclohexylmethylalcohol.

Workup

  1. customThe present compound was synthesized by a method similar to that in Example 207

Sources & evidence

ORD record
ord-23d1c2cbd554482c8ce64cd0759d7070
Source dataset
uspto-grants-2008_07
Patent number
US07402595B2

Reaction notes

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