1-(Chloromethoxy)-2-methoxyethane → HCID 69157487, compound

HRID 750228Notes

Reaction equation

HRID 750228 reaction equation
[CH3:1][O:2][C:3]([C:5]1[N:6]([CH2:23][C:24]2[CH:29]=[CH:28][C:27]([OH:30])=[CH:26][CH:25]=2)[C:7](=[O:22])[C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Br:21])=[CH:10][CH:9]=2)=[O:4].[CH3:31][O:32][CH2:33][CH2:34][O:35][CH2:36]Cl>>[CH3:1][O:2][C:3]([C:5]1[N:6]([CH2:23][C:24]2[CH:25]=[CH:26][C:27]([O:30][CH2:31][O:32][CH2:33][CH2:34][O:35][CH3:36])=[CH:28][CH:29]=2)[C:7](=[O:22])[C:8]2[C:13]([C:14]=1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)=[CH:12][C:11]([Br:21])=[CH:10][CH:9]=2)=[O:4]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 69156619HCID 69156619, compound

Product 1

HCID 69157487HCID 69157487, compound

Procedure

The present compound was synthesized by a method similar to that in Example 260 and using 6-bromo-2-(4-hydroxybenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid methyl ester (200 mg) and methoxyethoxymethylchloride. Colorless crystals (28 mg).

Workup

  1. customThe present compound was synthesized by a method similar to that in Example 260

Sources & evidence

ORD record
ord-3053f3c2624e4ea9a9b6bcd850ec7998
Source dataset
uspto-grants-2008_07
Patent number
US07402595B2

Reaction notes

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