4-Hydroxymethylpyridine → HCID 69155562, compound

HRID 750232Notes

Reaction equation

HRID 750232 reaction equation
[CH2:1]([N:8]1[C:17]([C:18]([OH:20])=[O:19])=[C:16]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([Br:27])[CH:14]=2)[C:9]1=[O:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:29]1[CH:34]=[CH:33][C:32]([CH2:35]O)=[CH:31][CH:30]=1>>[N:29]1[CH:34]=[CH:33][C:32]([CH2:35][O:19][C:18]([C:17]2[N:8]([CH2:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)[C:9](=[O:28])[C:10]3[C:15]([C:16]=2[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)=[CH:14][C:13]([Br:27])=[CH:12][CH:11]=3)=[O:20])=[CH:31][CH:30]=1

Participants

3

Reactant 2

HCID 114724-HydroxymethylpyridineHCID 230606482-benzyl-6-bromo-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid

Product 1

HCID 69155562HCID 69155562, compound

Procedure

The present compound was synthesized by a method similar to that in Example 200 and using 2-benzyl-6-bromo-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid (200 mg) and 4-pyridinemethanol. A colorless powder (160 mg).

Workup

  1. customThe present compound was synthesized by a method similar to that in Example 200

Sources & evidence

ORD record
ord-52188af946014f5db0ff6733e75bfc25
Source dataset
uspto-grants-2008_07
Patent number
US07402595B2

Reaction notes

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