Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750271Generated: October 27, 2026

THF diisopropyl ether → 6-bromo-2-(4-methanesulfonylbenzyl)-4-phenyl-3-propionyl-2H-isoquinolin-1-one

https://huagongshe.com/reaction/750271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTHF diisopropyl etherHCID 21940044—
Reactant6-bromo-3-(1-hydroxypropyl)-2-(4-methanesulfonylbenzyl)-4-phenyl-2H-isoquinolin-1-oneHCID 23060796—
Product6-bromo-2-(4-methanesulfonylbenzyl)-4-phenyl-3-propionyl-2H-isoquinolin-1-oneHCID 10218071—

Reaction Steps

In the same manner as in Example 311, the title compound was synthesized using 6-bromo-3-(1-hydroxypropyl)-2-(4-methanesulfonylbenzyl)-4-phenyl-2H-isoquinolin-1-one. Crystals (THF-diisopropyl ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07402595B2
Source datasetuspto-grants-2008_07
ORD IDord-2aba227c5072460d89197b2f27d3c6c0
Source noteuspto-grants-2008_07