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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750272Generated: November 1, 2026

Diisopropyl Ether → 6-chloro-3-hydroxymethyl-2-(4-methanesulfonylbenzyl)-4-phenyl-2H-isoquinolin-1-one

https://huagongshe.com/reaction/750272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropyl EtherHCID 7914—
Reactant6-Chloro-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acidHCID 23060778—
Product6-chloro-3-hydroxymethyl-2-(4-methanesulfonylbenzyl)-4-phenyl-2H-isoquinolin-1-oneHCID 23060872—

Reaction Steps

In the same manner as in Example 310, the title compound was synthesized using 6-chloro-2-(4-methanesulfonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic acid. Crystals (diisopropyl ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07402595B2
Source datasetuspto-grants-2008_07
ORD IDord-993cad074ed54205a6f2a9723f59dd9a
Source noteuspto-grants-2008_07