HCID 69031670, compound → HCID 69031120, compound

Participants

Reaction Steps

To a stirred solution of 5 (14.55 g, 31.86 mmol) in methylene chloride (100 ml) was added tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene]-[benzylidine]ruthenium (VI) dichloride (270 mg, 0.32 mmol), and the reaction mixture was stirred at room temperature for 2 days. The volatiles were removed under reduced pressure and the residue was purified by silica gel column chromatography (hexane:ethyl acetate=5:1) to give 6 (12.83 g, 94%) as a white semi-solid; 1H NMR (400 MHz, CDCl3) δ 7.47-7.21 (m, 15H), 5.93 (dd, J=5.6, 1.6 Hz, 1H), 5.73 (d, J=5.6 Hz, 1H), 5.31 (d, J=5.6 Hz, 1H), 4.56 (d, J=5.6 Hz, 1H), 3.59 (d, J=9.2 Hz, 1H), 3.15 (d, J=9.2 Hz, 1H), 3.02 (s, 1H), 1.32 (s, 3H), 1.21 (s, 3H).

Provenance & Evidence