HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 2,4-Dichloro-α-phenyl-5-pyrimidinemethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 5-Bromo-2,4-dichloropyrimidine | HCID 289973 | — |
| Product | 2,4-Dichloro-α-phenyl-5-pyrimidinemethanol | HCID 15053973 | 79% |
Reaction Steps
The compound was prepared from 5-bromo-2,4-dichloropyrimidine (Aldrich) and benzaldehyde (Aldrich) in 79% yield in an analogous manner as described in Example 1. 1H NMR (300 MHz, CDCl3) δ 8.91 (s, 1H), 7.36 (m, 5H), 6.06 (d, 1H, J=3.0 Hz), 2.48 (br m,1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405220B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-4ec3783ec1a34cc795bfb6bff7d60963 |
| Source note | uspto-grants-2008_07 |