HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Aminopropyl)-4-methylpiperazine → 3-(4-Bromo-2,3,6-trifluoro-benzyloxy)-5-{3-[3-(4-methyl-piperazin-1-yl)-propyl]-ureido}-isothiazole-4-carboxylic Acid Amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Aminopropyl)-4-methylpiperazine | HCID 78328 | — |
| Reactant | [3-(4-Bromo-2,3,6-trifluoro-benzyloxy)4-carbamoyl-isothiazol-5-yl]-carbamic acid phenyl ester | HCID 86588929 | — |
| Product | 3-(4-Bromo-2,3,6-trifluoro-benzyloxy)-5-{3-[3-(4-methyl-piperazin-1-yl)-propyl]-ureido}-isothiazole-4-carboxylic Acid Amide | HCID 10076619 | — |
Reaction Steps
The title compound was prepared from [3-(4-bromo-2,3,6-trifluoro-benzyloxy)-4-carbamoyl-isothiazol-5-yl]-carbamic acid phenyl ester and 3-(4-methyl-piperazin-1-yl)-propylamine by the procedure analogous to Example 1. MS (APCl, m/z): 565 and 567 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405218B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-4403296d548a441a8701468d622ab252 |
| Source note | uspto-grants-2008_07 |