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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750604Generated: October 25, 2026

4-Dimethylaminobutylamine → 5-[3-(4-Dimethylamino-butyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy) isothiazole-4-carboxylic acid amide

https://huagongshe.com/reaction/750604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-DimethylaminobutylamineHCID 77063—
Reactant[4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl esterHCID 54053016—
Product5-[3-(4-Dimethylamino-butyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy) isothiazole-4-carboxylic acid amideHCID 10366941—

Reaction Steps

The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and N,N-dimethyl-butane-1,4-diamine by the procedure analogous to Example 1. MS (APCl, m/z): 460 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405218B2
Source datasetuspto-grants-2008_07
ORD IDord-b9eb1b7b1b794c9da670b8b053426f3a
Source noteuspto-grants-2008_07