化工社化工社 化学情報印刷レポート · 研究参考用
4-(Bromomethyl)benzonitrile → {3-[2-(4-Cyano-benzyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methoxy-indol-1-yl}-acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| 反応物 | [3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-5-methoxy-indol-1-yl]-acetic acid tert-butyl ester | HCID 67316901 | — |
| 生成物 | {3-[2-(4-Cyano-benzyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-5-methoxy-indol-1-yl}-acetic acid | HCID 59753803 | — |
反応手順
The title compound was prepared by the method described for example 14 using the product from example 4, step c) and 4-cyanobenzyl bromide. MS: ESI (negative): 486 (M−H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07405215B2 |
| 出典データセット | uspto-grants-2008_07 |
| ORD ID | ord-b5240967f0684f4394a9ac56b5bf11c5 |
| 出典メモ | uspto-grants-2008_07 |