反应详情

温度

25 °C

Dissolved into 810 g of formic acid was 202.2 g of the methacrylate ester (25) obtained in Synthesis Example 1-1-1; and then, the resulting mixture was stirred at 25° C. for 16 hours. After formic acid was removed by distillation under reduced pressure, recrystallization was made from ethyl acetate to give 135.1 g of the intended product (Yield 81%).

1. customobtained in Synthesis Example 1-1-1
2. customAfter formic acid was removed by distillation under reduced pressure, recrystallization