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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750842Generated: November 3, 2026

3-Fluorophenol → HCID 59753906, compound

https://huagongshe.com/reaction/750842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluorophenolHCID 9743—
ReactantHCID 69198607HCID 69198607—
ProductHCID 59753906HCID 59753906—

Reaction Steps

2-Methylsulfonyl-4-(2,4-dichlorophenyl)-5-(4-chlorophenyl)pyrimidine from Reference Example 3 was reacted with 3-fluorophenol according to the procedure described in Example 74 to afford 2-(3-fluorophenyloxy)-4-(2,4-dichlorophenyl)-5-(4-chlorophenyl)pyrimidine: HPLC/MS: m/e=445 (M++1); Rt=4.50 min; 1H-NMR 400 MHz (CDCl3): δ 7.05. (m, 3H), 7.21-7.30 (m, 6H), 7.38-7.42 (m, 2H), 8.60 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405221B2
Source datasetuspto-grants-2008_07
ORD IDord-b13c7d48891648e9a4be92d9512b179c
Source noteuspto-grants-2008_07