(3-Chlorophenyl)boronic acid → HCID 59753958, compound

Participants

Reaction Steps

This derivative was prepared by the method described in Example 132 using 2-(3,4-difluorophenoxy)-4-methoxy-5-trifluoromethansulfonyl-6-[2,4-dichlorophenyl]pyrimidine (27 mg, 0.05 mmol) as described in Reference Example 17 and 3-chlorobenzeneboronic acid (Lancaster, 16 mg, 0.1 mmol). HPLC Rt=4.82 min. 1H-NMR 500 MHz (CDCl3): 3.88 (s, 3H), 6.45 (d, J=8 Hz, 1H), 6.51 (s, 1H), 6.67 (d, J=8 Hz, 1H), 6.71 (s, 1H), 6.95 (m, 1H), 7.05 (t, J=9 Hz, 1H), 7.8 (m, 2H), (7.39 s, 2H).

Provenance & Evidence