4-Fluorobenzohydrazide → 4-Fluoro-benzoic acid-(1-imino-ethyl)-hydrazide

HRID 750885Notes

Reaction equation

Cl.C(O[C:5](=[NH:7])[CH3:6])C.[F:8][C:9]1[CH:18]=[CH:17][C:12]([C:13]([NH:15][NH2:16])=[O:14])=[CH:11][CH:10]=1>>[NH:7]=[C:5]([N:15]([C:13](=[O:14])[C:12]1[CH:17]=[CH:18][C:9]([F:8])=[CH:10][CH:11]=1)[NH2:16])[CH3:6]

Participants

Reactant 2

HCID 99724-Fluorobenzohydrazide

HCID 2724290Ethanimidic acid, ethyl ester, hydrochloride (1:1)

Product 1

HCID 684925634-Fluoro-benzoic acid-(1-imino-ethyl)-hydrazide

Procedure

Prepared from 7.2 g (58 mmol) ethylacetimidate hydrochloride and 5.00 g (32 mmol) 4-fluoro-benzoic acid hydrazide analogously to the method described for intermediate product 1, Step a).

Sources & evidence

ORD record: ord-c3ccc84b53384571ba9e2a34737a1356
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07405232B2

Reaction notes

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