HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 66886384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-(4-Fluoro-phenyl)-5-methyl-[1,2,4]triazole | HCID 43166756 | — |
| Reactant | tert-butyl N-(4-chloro-2-methylbutan-2-yl)carbamate | HCID 57429079 | — |
| Catalyst | Tetrabutylammonium Iodide | HCID 67553 | — |
| Solvent | 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- | HCID 81646 | — |
| Product | HCID 66886384 | HCID 66886384 | — |
Reaction Steps
5.88 g (33 mmol) 3-(4-fluoro-phenyl)-5-methyl-[1,2,4]triazole are dissolved in 40 mL DMPU and reacted with 11.04 g (50 mmol) tert-butyl(3-chloro-1,1-dimethyl-propyl)-carbamate, 1.59 g (40 mmol, 60%) sodium hydride and 2.21 g (6 mmol) tetrabutylammonium iodide as described for intermediate product 1c).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405232B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-43acf2c4c99b4d0cb767577bf511beac |
| Source note | uspto-grants-2008_07 |