Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750900Generated: November 1, 2026

Sodium Azide → HCID 86591692, compound

https://huagongshe.com/reaction/750900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AzideHCID 33557—
ReactantHCID 86591693HCID 86591693—
SolventDimethylformamideHCID 6228—
ProductHCID 86591692HCID 8659169278%

Reaction Conditions

Temperature70 °C

Reaction Steps

The mixture of sodium azide (88.5 mmol) and (R)-{3-[4-(4,4-dimethoxy-3-fluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-methanesulfonate (29.6 mmol) in dimethylformamide (75 ml) was heated at 70° C. for 14 hours. The reaction mixture was poured on ice cold water, and the solid was filtered to afford title compound in 78% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405228B2
Source datasetuspto-grants-2008_07
ORD IDord-57304b70137243c09510eda880a9e82c
Source noteuspto-grants-2008_07