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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750902Generated: October 31, 2026

HCID 86591692, compound → HCID 69315286, compound

https://huagongshe.com/reaction/750902

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86591692HCID 86591692—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 69315286HCID 6931528689%

Reaction Steps

The suspension of (S)-{3-[4-(4,4-dimethoxy-3-fluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-azide (25.2 mmol) and 10% palladium on carbon (1.0 g) was in ethyl acetate (150 ml) was stirred at a room temperature under hydrogen atmosphere for 10 hours. The reaction mixture was filtered and the filtrate was concentrated to give a residue, which was purified on silica gel column chromatography to provide title compound in 89% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405228B2
Source datasetuspto-grants-2008_07
ORD IDord-1bba178a8e9a4f0a9b3bf610382be1de
Source noteuspto-grants-2008_07