反应详情

The mixture of 4-(4-trimethylsilyloxy-piperidin-1-yl)-3-fluoronitrobenzene (151 mmol), selectfluor (151 mmol) in acetonitrile was stirred for 4 hours. The solvent was removed under reduced pressure and to the residual mass was extracted into ethyl acetate water mixture. The combined organic layer was dried and removal of the solvent afforded title compound in 88% yield.

1. customThe solvent was removed under reduced pressure and to the residual mass
2. extractionwas extracted into ethyl acetate water mixture
3. customThe combined organic layer was dried
4. customremoval of the solvent