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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750909Generated: November 4, 2026

Sodium Azide → HCID 86591696, compound

https://huagongshe.com/reaction/750909

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AzideHCID 33557—
ReactantHCID 86591697HCID 86591697—
SolventDimethylformamideHCID 6228—
ProductHCID 86591696HCID 8659169678%

Reaction Conditions

Temperature70 °C

Reaction Steps

The mixture of sodium azide (67.0 mmol) and (R)-{3-[4-(4,4-dimethoxy-3-fluoropiperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-methanesulfonate (27.0 mmol) in dimethylformamide was heated at 70° C. for 14 hours. The reaction mixture was poured on ice cold water, and the solid was filtered to afford title compound in 78% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405228B2
Source datasetuspto-grants-2008_07
ORD IDord-6e8af273168244ecb66874c1697820b1
Source noteuspto-grants-2008_07