HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86591700, compound → HCID 69315393, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86591700 | HCID 86591700 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69315393 | HCID 69315393 | 88% |
Reaction Steps
The suspension of (S)-{3-[4-(4,4-dimethoxy-3,3-difluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-azide (10 mmol) and 10% palladium on carbon (0.15 g) was in ethyl acetate was stirred at a room temperature under hydrogen atmosphere for 10 hours. The reaction mixture was filtered and the filtrate was concentrated to give a residue, which was purified on silica gel column chromatography to provide title compound in 88% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405228B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-ec4a999694084d84839b3f33d677349f |
| Source note | uspto-grants-2008_07 |