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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 750916Generated: November 1, 2026

HCID 86591700, compound → HCID 69315393, compound

https://huagongshe.com/reaction/750916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86591700HCID 86591700—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 69315393HCID 6931539388%

Reaction Steps

The suspension of (S)-{3-[4-(4,4-dimethoxy-3,3-difluoropiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-azide (10 mmol) and 10% palladium on carbon (0.15 g) was in ethyl acetate was stirred at a room temperature under hydrogen atmosphere for 10 hours. The reaction mixture was filtered and the filtrate was concentrated to give a residue, which was purified on silica gel column chromatography to provide title compound in 88% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405228B2
Source datasetuspto-grants-2008_07
ORD IDord-ec4a999694084d84839b3f33d677349f
Source noteuspto-grants-2008_07