HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → HCID 69315928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 24885852 | HCID 24885852 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69315928 | HCID 69315928 | 35% |
Reaction Steps
The mixture of (S)-N-{3-[4-(4-cyanomethylidene-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine (0.12 mmol), allyl bromide (0.18 mmol), and potassium carbonate (0.25 mmol) in tetrahydrofuran was heated at reflux temperature for 12 hours. Solvent evaporation and purification to provided the title compound in 35% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405228B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-11efdd1d8a2f4a4197eda4ebbf433d00 |
| Source note | uspto-grants-2008_07 |