HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trichloroacetic Acid → (S)-N-{3-[4-(4-(1-Cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-trichloroacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trichloroacetic Acid | HCID 6421 | — |
| Reactant | (S)-N-{3-[4-(4-(1-cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine | HCID 69315435 | — |
| Product | (S)-N-{3-[4-(4-(1-Cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-trichloroacetamide | HCID 24887808 | 45% |
Reaction Steps
The title compound was prepared by following the procedure of Example 29 and by using (S)-N-{3-[4-(4-(1-cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine and trichloroacetic acid in 45% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405228B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-44bab824c956480ba0f36cc6d4ab889f |
| Source note | uspto-grants-2008_07 |