HCID 69310439, compound → HCID 69311858, compound

HRID 750933Notes

Reaction equation

HRID 750933 reaction equation
[C:1]([CH:3]=[C:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[CH2:20][C@H:19]([CH2:21][OH:22])[O:18][C:17]3=[O:23])=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)#[N:2]>[Pd]>[C:1]([CH2:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:11]=[CH:12][C:13]([N:16]3[CH2:20][C@H:19]([CH2:21][OH:22])[O:18][C:17]3=[O:23])=[CH:14][CH:15]=2)[CH2:6][CH2:5]1)#[N:2]

Participants

3

Reactant 1

HCID 69310439HCID 69310439, compound

Product 1

HCID 69311858HCID 69311858, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Conditions

Temperature
30 °C

Procedure

The suspension of (R)-{3-[4-(4-cyanomethylidenepiperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-alcohol (0.11 mmol), 10% palladium on carbon (0.1 g) tetrahydrofuran was stirred under atmospheric hydrogen pressure at 30° C. for overnight.

Sources & evidence

ORD record
ord-fc5c6d6948494a3c82d716a9f288b414
Source dataset
uspto-grants-2008_07
Patent number
US07405228B2

Reaction notes

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