HCID 69313319, compound → HCID 69313067, compound

HRID 750934Notes

Reaction equation

HRID 750934 reaction equation
[C:1]([CH:3]=[C:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[CH2:20][C@@H:19]([CH2:21][N:22]4[CH:26]=[C:25]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[N:24]=[N:23]4)[O:18][C:17]3=[O:32])=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)#[N:2]>[Pd]>[C:1]([CH2:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[CH2:20][C@@H:19]([CH2:21][N:22]4[CH:26]=[C:25]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[N:24]=[N:23]4)[O:18][C:17]3=[O:32])=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)#[N:2]

Participants

3

Reactant 1

HCID 69313319HCID 69313319, compound

Product 1

HCID 69313067HCID 69313067, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Conditions

Temperature
30 °C

Procedure

The suspension of (S)-1-{3-[4-(4-cyanomethylidene-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-4-carboethoxy-1,2,3-triazole (0.14 mmol), 10% palladium on carbon (0.1 g) tetrahydrofuran was stirred under atmospheric hydrogen pressure at 30° C. for overnight.

Sources & evidence

ORD record
ord-e2b2c11aba534f369361ccad94a41c54
Source dataset
uspto-grants-2008_07
Patent number
US07405228B2

Reaction notes

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