HRID751121

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21863450

未命名化合物

结构：CC(C)(C)OC(=O)N1CC[C@@H](O[Si](C)(C)C(C)(C)C)[C@@]1(C)CO

HCID68457239

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)O[C@@H]1CCN[C@]1(C)CO.O=C(O)C(F)(F)F

HCID68459451

未命名化合物

PROCEDURE

实验过程

(2R,3R)-3-(tert-Butyldimethyl-silanyloxy)-2-hydroxymethyl-2-methylpyrrolidine-1-carboxylic acid tert-butyl ester (58B) (269 mg, 0.78 mmol) was stirred in 17% TFA/CH2Cl2 (6 mL) for 30 min. The reaction was concentrated to provide a brown oil (334 mg). LC/MS m/z 246 [M+H]+

WORKUP

后处理

concentrationThe reaction was concentrated