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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751184Generated: October 31, 2026

Lithium Hydroxide → {6-[5-(3-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/751184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{6-[5-(3-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl esterHCID 68822183—
Product{6-[5-(3-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acidHCID 11502579—

Reaction Steps

In analogy to the procedure described for example 1 e], {6-[5-(3-trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as green crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405236B2
Source datasetuspto-grants-2008_07
ORD IDord-f27414bb2a8a44edbcfb8c5dcbb8695b
Source noteuspto-grants-2008_07