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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751194Generated: October 26, 2026

Lithium Hydroxide → {4-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/751194

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{4-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl esterHCID 68821972—
Product{4-[5-(4-Trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acidHCID 11560734—

Reaction Steps

In analogy to the procedure described for example 1 e], {4-[5-(4-trifluoromethoxy-phenyl)-pent-4-ynyloxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405236B2
Source datasetuspto-grants-2008_07
ORD IDord-60a78dd34c7446acb1221530ef54348a
Source noteuspto-grants-2008_07