HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-iodo-4-(trifluoromethyl)- → 2-(1H-indol-6-yl)-N-[3-(4-trifluoromethyl-phenyl)-prop-2-ynyl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-iodo-4-(trifluoromethyl)- | HCID 67993 | — |
| Reactant | 2-(1H-Indol-6-yl)-N-prop-2-ynyl-acetamide | HCID 86095505 | — |
| Product | 2-(1H-indol-6-yl)-N-[3-(4-trifluoromethyl-phenyl)-prop-2-ynyl]-acetamide | HCID 68823246 | — |
Reaction Steps
In analogy to the procedure described for example 8 a], 2-(1H-indol-6-yl)-N-prop-2-ynyl-acetamide (example 13 a]) was reacted with 4-iodobenzotrifluoride in the presence of PdCl2(Ph3P)2 and cuprous iodide to give the title compound as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405236B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-c477c934415d4323a955949b1619199d |
| Source note | uspto-grants-2008_07 |