HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → [6-({Methyl-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-carbamoyl}-methyl)-indol-1-yl]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | [6-({Methyl-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-carbamoyl}-methyl)-indol-1-yl]-acetic acid ethyl ester | HCID 68822717 | — |
| Product | [6-({Methyl-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-carbamoyl}-methyl)-indol-1-yl]-acetic acid | HCID 68821520 | — |
Reaction Steps
In analogy to the procedure described for example 1 e], [6-({methyl-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-carbamoyl}-methyl)-indol-1-yl]-acetic acid ethyl ester was treated with LiOH to obtain the title compound as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405236B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-f1c08c56d78c413aa4e0f3d427929685 |
| Source note | uspto-grants-2008_07 |