HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,N',N'-Tetramethylazodicarboxamide → HCID 68821733, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,N',N'-Tetramethylazodicarboxamide | HCID 4278 | — |
| Reactant | Tributylphosphine | HCID 13831 | — |
| Reactant | (6-Hydroxy-indol-1-yl)-acetic acid ethyl ester | HCID 68821422 | — |
| Reactant | HCID 68826125 | HCID 68826125 | — |
| Product | HCID 68821733 | HCID 68821733 | — |
Reaction Steps
In analogy to the procedure described for example 1 d], (6-hydroxy-indol-1-yl)-acetic acid ethyl ester (example 1 c]) was reacted with [rac]-6-(4-trifluoromethoxy-phenyl)-hex-5-yn-2-ol in the presence of N,N,N′,N′-tetramethyl azodicarboxamide and tributylphosphine to give the title compound as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405236B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-a503c9575e174da0b48128029aafa014 |
| Source note | uspto-grants-2008_07 |