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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751340Generated: October 25, 2026

Piperazine → 2-(piperazin-1-yl)-1-methyl-1H-indole-3-carboxaldehyde

https://huagongshe.com/reaction/751340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant2-Chloro-1-methyl-1H-indole-3-carbaldehydeHCID 314792—
Product2-(piperazin-1-yl)-1-methyl-1H-indole-3-carboxaldehydeHCID 5975474524%

Reaction Steps

2-Chloro-1-methyl-1H-indole-3-carboxaldehyde (1.0 g, 5.5 mmol) is reacted with piperazine as described in Example 2 to yield the title compound (24%) as an orange-brown solid. MS 244 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405300B2
Source datasetuspto-grants-2008_07
ORD IDord-d886ef110fd64bfda4220f6de74d85de
Source noteuspto-grants-2008_07