HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 2-imidazol-1-yl-1-phenyl-1H-indole-3-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2-chloro-1-phenyl-1H-indole-3-carbaldehyde | HCID 314793 | — |
| Product | 2-imidazol-1-yl-1-phenyl-1H-indole-3-carboxaldehyde | HCID 59754757 | 12% |
Reaction Steps
2-Chloro-1-phenyl-1H-indole-3-carboxaldehyde is reacted with imidazole as described in Example 1 to afford 2-imidazol-1-yl-1-phenyl-1H-indole-3-carboxaldehyde (12% yield) as a white solid. LC/MS: 288 (M+H); RT 2.55 min; NMR (CDCl3): 9.94 (1H, s), 8.45 (1H, d), 7.63 (1H, s), 7.35-7.54 (6H, m), 7.17-7.29 (2H, m), 7.12 (1H, s), 7.03 (1H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405300B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-f65f722c742749bf8cb85665b0093152 |
| Source note | uspto-grants-2008_07 |