Piperazine → HCID 11338474, compound

Participants

Reaction Steps

2-chloro-1-(4-phenoxyphenyl)-1H-indole-3-carboxaldehyde is reacted with piperazine as described in Step 2 of Example 29 to afford 1-(4-phenoxyphenyl)-2-piperazin-1-yl-1H-indole-3-carboxaldehyde (40% yield). ESI/MS 398 (M+H); RT=2.95 min; NMR (CDCl3) 10.28 (1H, s); 8.28 (1H, d, J=9 Hz); 7.46-7.10 (1H, m); 7.00 (1H, d, J=9 Hz); 3.31 (4H, m); 2.81 (4H, m).

Provenance & Evidence