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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751436Generated: October 31, 2026

HCID 59754783, compound → HCID 59754788, compound

https://huagongshe.com/reaction/751436

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59754783HCID 59754783—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
SolventEthyl AcetateHCID 8857—
ProductHCID 59754788HCID 59754788—

Reaction Steps

To a solution of Ethyl (E)-3-[1-(4-chloro-benzyl)-5-methoxy-1H-pyrrolo[2,3-b]pyridin-2-yl]-acrylate (100 mg, 0.270 mmol) in a mixture of EtOH (2 mL) and EtOAc (2 mL) was added Pd/C (˜15 mg) and maintained under an atmosphere of H2 for 36 hrs. The resulting slurry was filtered through celite eluting with EtOAc, and the solvent evaporated to afford the title acid as a green oil used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405302B2
Source datasetuspto-grants-2008_07
ORD IDord-9c421509af064e81965d16e50ad0cdc0
Source noteuspto-grants-2008_07