HCID 69270136, compound → HCID 69269366, compound

Participants

Reaction Conditions

Reaction Steps

Add active manganese dioxide (0.8 g, 9.0 mmol) to a solution of benzyl-[1-(pyridin-4-yl)-2,3-dihydro-1H-indol-7-ylmethyl]carbamic acid tert-butyl ester (0.39 mg, 0.94 mmol) in toluene. Stir the mixture at 90° C. for 16 hours. Cool and filter, then concentrate the filtrate. Purify by chromatography (silica gel; hexane/ethyl acetate; 3:1 to 0:1) to isolate a solid as the title compound (200 mg, 50%). MS (ESI) m/z 414 (M+H)+.

Provenance & Evidence