HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidin-4-ol → [1-(R)-(4-Fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl] carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidin-4-ol | HCID 79341 | — |
| Reactant | (2R)-2-(((tert-butoxy)carbonyl)amino)-3-(4-fluorophenyl)propanoic acid | HCID 2734493 | — |
| Product | [1-(R)-(4-Fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl] carbamic acid tert-butyl ester | HCID 21970173 | — |
Reaction Steps
The title compound was prepared according to EXAMPLE 231 but using Boc-3-(4-fluorophenyl)-(R)-alanine and 4-hydroxypiperidine. m/z (ES+)=367.34 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405210B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-77f6e73ef9714928bd01e93f74b58395 |
| Source note | uspto-grants-2008_07 |