HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tricyclo(3.3.1.13,7)dec-1-ylmethylamine → (+/-)-1-(1-Adamantylmethyl)-4-(hydroxymethyl)-4-isobutylimidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tricyclo(3.3.1.13,7)dec-1-ylmethylamine | HCID 86625 | — |
| Reactant | (+/-)-2-(Tert-butoxycarbonylamino)-2-(hydroxymethyl)-4-methylpentanoic acid | HCID 78067738 | — |
| Product | (+/-)-1-(1-Adamantylmethyl)-4-(hydroxymethyl)-4-isobutylimidazolidin-2-one | HCID 68472064 | — |
Reaction Steps
The title compound was prepared following procedures analogous to those described in Example 27 using (±)-2-(tert-butoxycarbonylamino)-2-(hydroxymethyl)-4-methylpentanoic acid and 1-(aminomethyl)adamantane. MS m/z=321.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835426B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-be24594330af48f5870c8035a084a492 |
| Source note | uspto-grants-2014_09 |