反应详情

The title compound was prepared as outlined in EXAMPLE 1 from 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 18) and 2-thiophen-2-ylethylamine. The product was purified by chromatography on silica gel eluting with methanol/dichloromethane (3:97) to give the title compound as a yellow solid. δH (CD3OD): 3.16 (2H, t), 3.65 (2H, t), 6.89–6.94 (2H, m), 7.03 (1H, s), 7.20 (1H, d), 7.66 (1H, s), 8.57 (1H, s); m/z (ES+)=306 [M+H]+.

1. customThe title compound was prepared
2. customThe product was purified by chromatography on silica gel eluting with methanol/dichloromethane (3:97)