2-Phenoxyethanamine → 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid (2-phenoxyethyl)amide

HRID 751689Notes

Reaction equation

HRID 751689 reaction equation
[NH:1]1[C:5]2=[CH:6][N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[C:2]1[C:10]([OH:12])=O.[O:13]([CH2:20][CH2:21][NH2:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[O:13]([CH2:20][CH2:21][NH:22][C:10]([C:2]1[NH:1][C:5]2=[CH:6][N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=1)=[O:12])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 156512-PhenoxyethanamineHCID 218190021H-Pyrrolo(2,3-c)pyridine-2-carboxylic acid

Product 1

HCID 111851331H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid (2-phenoxyethyl)amide

Procedure

The title compound was prepared as outlined in EXAMPLE 1 from 1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 15) and 2-phenoxyethylamine to give the title compound as a pale yellow solid. δH (CD3OD): 3.81 (2H, t), 4.18 (2H, t), 6.89–6.97 (3H, m), 7.14 (1H, s), 7.26 (2H, t), 7.65 (1H, d), 8.10 (1H, d), 8.78 (1H, s); m/z (ES+)=282 [M+H]+.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-4b5525a929634768b68d3a01591242ea
Source dataset
uspto-grants-2008_07
Patent number
US07405210B2

Reaction notes

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