HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(piperidin-4-yl)methanesulfonamide hydrochloride → 5-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid [1-(S)-(4-fluorobenzyl)-2-(4-methanesulfonylaminopiperidin-1-yl)-2-oxoethyl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(piperidin-4-yl)methanesulfonamide hydrochloride | HCID 20569935 | — |
| Reactant | 2-(S)-[(5-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carbonyl)amino]-3-(4-fluorophenyl)propionic acid | HCID 59753699 | — |
| Product | 5-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid [1-(S)-(4-fluorobenzyl)-2-(4-methanesulfonylaminopiperidin-1-yl)-2-oxoethyl]amide | HCID 59753531 | — |
Reaction Steps
The title compound was prepared according to EXAMPLE 229 from 2-(S)-[(5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carbonyl)amino]-3-(4-fluorophenyl)propionic acid (EXAMPLE 228) and N-piperidin-4-yl methanesulfonamide hydrochloride (Preparation 92). Purification gave the title compound as an off-white powder. m/z (ES+)=522.30 [M+H]+; RT=3.29 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07405210B2 |
| Source dataset | uspto-grants-2008_07 |
| ORD ID | ord-6082bc836ed1489c8e47d43204ad9cdd |
| Source note | uspto-grants-2008_07 |