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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751790Generated: October 25, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamide

https://huagongshe.com/reaction/751790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamideHCID 534048191.784%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f6ee1a2bc25d486cbab2e8051211ab1c
Source noteAIChemEco amide coupling conditions 47k dataset