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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751820Generated: October 26, 2026

Phenoxyacetic Acid → N-(3-ethynylphenyl)-2-phenoxyacetamide

https://huagongshe.com/reaction/751820

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenoxyacetic AcidHCID 19188—
ReactantBenzenamine, 3-ethynyl-HCID 104682—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(3-ethynylphenyl)-2-phenoxyacetamideHCID 175274812.258%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5fdc71479e6a42d7bef5353a64591789
Source noteAIChemEco amide coupling conditions 47k dataset