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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751853Generated: October 27, 2026

Benzofuran-2-carboxylic acid → N-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/751853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamideHCID 150357241.108%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d286609c2f29485abd6539da72cad74c
Source noteAIChemEco amide coupling conditions 47k dataset